Palmetto rolled, while Manatee had a little tougher time.
No matter, both teams won Friday night to advance to their respective state semifinals.
The Tigers never trailed and led 28-0 at halftime, en route to a 42-21 victory at Immokalee. They'll host Miami Norland next Friday at 7:30 p.m.
The Hurricanes survived a tough test at home against Fort Pierce Central 13-10. They'll host Palm Beach Gardens Dwyer next Friday, also at 7:30 p.m.
Palmetto quarterback Trent Miller threw five touchdown passes in the rout of the Indians, including two to Jonathan Saxon and one each to Terrance Mann, Josh Hicks and Shaquille Harris.
Hicks added a touchdown run.
Manatee struggled on offense, scoring just two field goals, a 43-yarder and 39-yarder from Nick Tankersley.
The Hurricanes' lone touchdown came on a Roshaun Goff fumble recovery in the end zone.